Herpes
Description of Herpes:
Herpes simplex is a viral disease caused by Herpes simplex viruses; both
herpes simplex virus 1 (HSV-1) and herpes simplex virus 2 (HSV-2) cause herpes
simplex. Infection with the herpes virus is categorized into one of several
distinct disorders based on the site of infection. Oral herpes, the visible
symptoms of which are colloquially called cold sores, infects the face and mouth.
Oral herpes is the most common form of infection. Infection of the genitals,
commonly known as herpes, is the second most common form of herpes. Other
disorders such as herpetic whitlow, herpes gladiatorum, ocular herpes
(keratitis), cerebral herpes infection encephalitis, Mollaret's meningitis,
neonatal herpes, and possibly Bell's palsy are all caused by herpes simplex
viruses.
Herpes viruses cycle between periods of active disease—presenting as blisters
containing infectious virus particles—that last 2–21 days, followed by a
remission period, during which the sores disappear. Genital herpes, however, is
often asymptomatic, though viral shedding may still occur. After initial
infection, the viruses move to sensory nerves, where they reside as life-long,
latent viruses. Causes of recurrence are uncertain, though some potential
triggers have been identified. Over time episodes of active disease reduce in
frequency.
Herpes simplex is most easily transmitted by direct contact with a lesion or
the body fluid of an infected individual. Transmission may also occur through
skin-to-skin contact during periods of asymptomatic shedding. Barrier protection
methods are the most reliable, but not failsafe, method of preventing
transmission of herpes. Oral herpes is easily diagnosed if the patient presents
with visible sores or ulcers. Early stages of orofacial herpes and genital
herpes are harder to diagnose; laboratory testing is usually required.
Prevalence of HSV infections varies throughout the world. Poor hygiene,
overcrowding, lower socioeconomic status, and birth in an undeveloped country
have been identified as risk factors associated with increased HSV-1 childhood
infection. Additional studies have identified other risk factors for both types
of HSV.
There is currently no cure for herpes; no vaccine is currently available to
prevent or eliminate herpes, although vaccines of varying effectiveness are
currently in phase III trials. Also, treatments are available to reduce viral
reproduction and shedding, prevent the virus from entering the skin, and
alleviate the severity of symptomatic episodes.
Specific Herpes Information
Articles, questions and answers.